I.against [美 əˈɡɛnst, 英 əˈɡɛnst, əˈɡeɪnst]介词against often appears as the second element of certain verb structures in English (come up against, guard against, turn against, etc). For translations, see the relevant verb entry (come, guard, turn, etc).
For instance, the public interest may tell against the grant of a mining lease even though the particular interests are the only interests primarily affected.