Foci morphology and evolution appears to be the result of an altered regulatory circuit composed of the same patterning mechanisms conserved in insect wing patterning.
These were pointed at one another (through holes in the tube of the telescope, or by removing the telescope from its mount) so that the crosshairs in their foci coincided.
In mice experiment, mice supplemented with inulin showed reduced carcinogen-induced aberrant crypt foci in the distal colon during exposure to pathogens or tumor inducers.