This relationship exists because the drugs bind directly to cavities in proteins of the central nervous system, although several theories of general anaesthetic action have been described.
The court further held that the word search, when used in the context of the powers of search and seizure, does not include an operation under general anaesthetic.
They assumed that solubilization of lipophilic general anaesthetic in lipid bilayer of the neuron causes its malfunction and anaesthetic effect when critical concentration of anaesthetic is reached.
Although protein targets for anaesthetics have been partly identified the exact nature of general anaesthetic-protein interactions still remains a mystery.
Normal interactions between residues in protein regions (loops) at the water-lipid interface that play critical roles in protein functions and agonist binding may be disrupted by general anaesthetic.
