By the end of the series, despite the turmoil she's faced and her professor's initial displeasure at her consistent tardiness, she graduates with her degree.
If a stranger tickles a child without any preliminaries, catching the child by surprise, the likely result will be not laughter but withdrawal and displeasure.
Droughts, earthquakes, volcanic eruptions, etc. were seen as a sign of anger or displeasure by deities, and sacrifices were supposed to lessen the divine ire.