The three presidents depicted in the movie are charismatic, moral and unselfish, although they agonize over their choices between public interest and personal happiness.
This is the same receptor that psychedelic drugs agonize to various degrees, which explains the correlation between psychedelic drugs and schizophrenia.
Many social scientists in other disciplines often agonize over the legitimacy of their work as science, and consequently emphasize the importance of detachment, objectivity, abstraction, and quantifiability in their work.