Perhaps categorization is more appropriately conducted using the flexible methodology of fuzzy logic insofar as the categories tend to overlap and ambiguity.
The use of fuzzy logic is especially relevant in gene regulatory networks, as the modeling of protein binding strength often requires non-binary variables.
Such an approach is sometimes called degree-theoretic semantics by logicians and philosophers, but the more usual term is fuzzy logic or many-valued logic.
Many other researchers provided solutions using concepts from several control areas such as robust control, optimal stochastic control, model predictive control, fuzzy logic etc.