It is also employed in no sutures corneal transplantation, pterygium excision with amniotic membrane or conjunctival autograft, and in ocular trauma for corneal or conjunctival defects.
One common culprit is corneal abrasions, caused by debris such as dust or sand scratching the surface of the cornea - the clear film that covers the front of the eye.
Corneal opacification occurred in both transgenic lines early in development due to greatly increased expression of perlecan, fibronectin and thrombospondin-1 in the corneal mesenchyme.