Although silanization of silicate surfaces was introduced more than 40 years ago, the process of formation of smooth layers on surfaces is still poorly understood.
Tensile strength may be highly improved by a chemical surface treatment of the particles, such as silanization, which allows the formation of strong bonds between glass particles and epoxy matrix.
The researchers produced cyano-, mercapto- and fluoro-functionalized glass vials by altering the interior surface using a silanization method, and then observed crystallization of the drug from supersaturated ethanol solutions.
