Angular cheilitis often represents an opportunistic infection of fungi and/or bacteria, with multiple local and systemic predisposing factors being involved in the initiation and persistence of the lesion.
In horses, the condition remains a fatal disease, as the animal inevitably succumbs to an opportunistic infection within the first four to six months of life.
Be aware that it should be kept away from excessive moisture that will encourage growth of an opportunistic infection, and should receive good airflow at this time.