They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.
They also established that extensive periods of artificial respiration did not allow for detoxification to occur and natural neuromuscular functioning to resume.
The program provides medical detoxification followed by primary treatment, including a 1-year continuing care plan designed specifically around the needs of each client.
Both detoxification with subsequent abstinence-oriented treatment and substitution maintenance treatment are essential components of an effective treatment system for people with opioid dependence.