When a researcher risks harm to a willing volunteer to do research with the intent to develop knowledge which will better humanity, this may be a practice of beneficence.
It is of interest as an early example of private beneficence for the benefit of impoverished women which has continued its mission for more than a century.
Likewise, nonmaleficence is maximized, by maximizing autonomy, beneficence, and justice and beneficence is maximized, by maximizing autonomy, nonmaleficence, and justice.