Studies have indicated alcohol may raise levels of good cholesterol and be beneficial to blood vessels, while antioxidants in wine are thought to protect arteries.
Oral administration (as succinate) suffers from poor bioavailability, partly due to presystemic metabolismsome of it gets broken down in the stomach and bloodstream before it reaches the target arteries.
For patients with coronary artery disease, a physician may recommend a bypass to reroute blood around blocked arteries to restore and improve blood flow and oxygen to the heart.