His research includes investigation of hormonal control of gene regulation, and circadian rhythm, and post-translation protein modifications such as methylation and acetylation.
Also, within the cranium, the pineal gland, which attaches to the thalamus, controls the body's 24 hour rhythms circadian rhythm through the release of melatonin.
This has prompted researchers to speculate involvement, or dysfunction of the brain's hypothalamus, which controls the body's biological clock and circadian rhythm.
This system allowed an exquisitely precise circadian rhythm of luminescence to be measured from cell populations and even from single cyanobacterial cells.