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多雪
Angiotensin II
angiotensin II [ˌændʒɪəˈtensɪn] 名词
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互联网提供的例句(未经PONS编辑处理)
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An in vivo mouse model, in which implanted minipumps continuously release angiotensin II leading to the development of hypertrophy and fibrosis of the left heart, was established for future tests on the living organ for the proof of efficacy for the various decoy ODNs.
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www.ngfn.de
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Für zukünftige Tests am lebenden Organ wurde ein in vivo-Modell für den Wirksamkeitsnachweis der verschiedenen Decoy-ODN in der Maus etabliert, bei dem implantierte Minipumpen kontinuierlich Angiotensin II freisetzen, was bei den Tieren zur Entwicklung einer Hypertrophie und Fibrose des linken Herzens führt.
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These results show, however, that ACE is enzymatically active and produces other active products apart from angiotensin II, for example in the testes.
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www.mdc-berlin.de
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Diese Ergebnisse zeigen aber, dass ACE außer Angiotensin II weitere Stoffe produziert und enzymatisch aktiv ist, so zum Beispiel in den Hoden.
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However, if in the mice not the enzyme itself, but rather a product of ACE – namely the hormone angiotensin II – was suppressed, they could continue to reproduce.
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www.mdc-berlin.de
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Wurde bei den Mäusen dagegen nicht das Enzym selbst, sondern nur ein Produkt von ACE, nämlich das Hormon Angiotensin II, unterdrückt, konnten sie sich weiterhin fortpflanzen.
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Until now it was thought that ACE mainly exerts its effect through the production of angiotensin II.
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www.mdc-berlin.de
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Bislang nahmen Wissenschaftler an, dass ACE vorwiegend durch die Produktion von Angiotensin II seine Wirkung entfaltet.
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A second research focus is the investigation of putative proarteriosclerotic mechanisms like increased oxidative stress or augmented uptake of oxidized low-density lipoprotein ( oxLDL ) by the vasoactive peptides endothelin-1, angiotensin II and aldosterone in endothelial cells.
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www.uniklinikum-dresden.de
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Einen weiteren Arbeitsschwerpunkt bildet die Aufklärung von potentiell proarteriosklerotischen Mechanismen wie erhöhtem oxidativen Stress oder vermehrter Aufnahme von oxidativ modifiziertem Low-Density-Lipoprotein durch Peptide wie Endothelin-1, Angiotensin II und Aldosteron in Endothelzellen.
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