Updated every three years, they currently are: low-income, $1,005 or less; lower-middle-income, to $3,975; upper-middle-income, to $12,275; and high-income, more than $12,275.
At $5 per dose the estimated cost per life saved was $3,015, $9,951 and $11,296 in low-, lower-middle-, and upper-middle-income countries, respectively.
The growth has been driven largely by demand from students from upper-middle-income economies and countries with large national scholarship programmes.
Typical regulations in low-income countries required 13 documents from domestic regulatory agencies as compared to six signatures in high income countries, nine in upper-middle-income and ten in low-middle-income countries.