He was also responsible for the identification of nitric oxide as a biological mediator and the elucidation of the metabolic pathway leading to its synthesis.
With his group, he made important and original advances in the elucidation of its anatomy and electrophysiology, cytochemistry, as well as its nervous control.
He is known for the recognition and elucidation of the intramolecular nature of radiationless dissipation of energy in molecules of large and medium size.
Likewise, in scientific modeling, simplifying assumptions permit illustration or elucidation of concepts thought relevant within the sphere of inquiry.