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往日
Totipotenz
totipotency [ˌtəʊtɪˈpəʊtənsi], totipotence 名词
totipotency
Totipotenz
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Scientists from Hans Schöler ’ s team at the Max Planck Institute for Molecular Biomedicine in Münster have now been able to demonstrate that an egg cell does not require Oct4 to develop into a complete organism ( totipotency ).
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www.mpg.de
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Jetzt haben Wissenschaftler um Hans Schöler vom Max-Planck-Institut für molekulare Biomedizin in Münster gezeigt, dass Oct4 nicht erforderlich ist, damit eine Eizelle sich zu einem kompletten Organismus entwickeln kann ( Totipotenz ).
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“ In other words, it was still possible to activate the totipotency of the fertilised egg cells, as in normal fertilisation, ” he adds.
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www.mpg.de
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„ Die Fähigkeit, die befruchtete Eizelle zur Totipotenz zu aktivieren, wie es bei der normalen Befruchtung geschieht, war also nicht beeinträchtigt “, so Wu weiter.
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To study the role of Oct4 in the transition from totipotency to pluripotency, the Max Planck researchers had to deactivate Oct4 in the egg cell.
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www.mpg.de
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Um den Einfluss von Oct4 im Übergang von Totipotenz zu Pluripotenz zu untersuchen, mussten die Max-Planck-Forscher Oct4 in der Eizelle ausschalten.
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“ Our study shows that cloning leads to totipotency with or without Oct4, while reprogramming cells for pluripotency is not possible without Oct4, ” Hans Schöler explains.
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www.mpg.de
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„ Unsere Studie zeigt, dass das Klonen unabhängig von Oct4 zur Totipotenz führt, wohingegen das Reprogrammieren zur Pluripotenz durch Oct4 überhaupt erst ermöglicht wird “, erläutert Hans Schöler.
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