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Proteasom

proteasome [ˈprəʊtɪəsəʊm] 名词

proteasome
Proteasom

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[...]
Some tumors contain activated forms of NF-kB, and the proteasome plays an important role in this activation, because it catalyzes the proteolytic generation of sub-NF-kB p50 from an inactive precursor r150 and destruction of inhibitory proteins LkB.
[...]
pharma-base.ru
[...]
Einige Tumoren enthalten Formen der NF-kB und dem Proteasom aktiviert spielt eine wichtige Rolle in dieser Aktivierung, weil es die proteolytische Generation von Unter-katalysiert-NF-kB p50 von einer inaktiven Vorstufe R150 und Vernichtung von inhibitorischen Proteinen LKB.
[...]
pharma-base.ru
[...]
These bacteria produce a small molecule that kills affected cells by disabling proteasomes, which serve as their waste processing plants.
[...]
www.tum.de
[...]
Dieses produziert ein kleines Molekül, das befallene Zellen abtötet indem es die zelluläre Müllverwertungsanlage, das Proteasom, lahm legt.
[...]
www.tum.de
[...]
The key can be removed from the lock and the proteasome can resume its work.
[...]
www.biochemie.ch.tum.de
[...]
So läst sich der Schlüssel wieder aus dem Schloss entfernen und das Proteasom kann seine Arbeit wieder aufnehmen.
[...]
www.biochemie.ch.tum.de
[...]
Due to its significant role in the growth of cancer cells, in recent years the proteasome has taken center stage in pharmacological research as a starting point for cancer medication.
[...]
www.tum.de
[...]
Wegen seiner bedeutenden Rolle für das Wachstum von Krebszellen ist das Proteasom in den letzten Jahren vor allem als Ansatzpunkt für Krebsmedikamente in den Fokus der pharmakologischen Forschung gerückt.
[...]
www.tum.de
[...]
It could be shown that the proteasome is composed of two complex components, the cylindric 20S core particle ( 20S proteasome ) and a 19S cap particle which docks onto both ends of the 20S proteasome to yield the 26S proteasome.
[...]
www.uni-stuttgart.de
[...]
So konnte gezeigt werden, daß das Proteasom aus zwei komplexen Teilkomponenten besteht, dem zylindrischen 20S Kernpartikel ( oder auch 20S Proteasom ) sowie einem 19S Cap-Partikel, der an die Enden des 20S Kernpartikels andockt.
[...]
www.uni-stuttgart.de

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