Some ruminant animals, for example cattle, showed no change in liver enzyme activities or any clinical signs of poisoning when fed plants containing pyrrolizidine alkaloids.
Moreover, much might be learned by coordinating these efforts with that of the metagenomic analysis of the hoatzin foregut ruminant bacterial microflora.
Mitigation options for reducing methane emission from ruminant enteric fermentation include genetic selection, immunization, rumen defaunation, diet modification and grazing management, among others.