Exterior lesions are restricted to the non-feathered parts of the body, usually the face and legs and are characterized by proliferative and necrotizing dermatitis.
A nerve biopsy can lead to the discovery of necrotizing vasculitis, amyloidosis, sarcoidosis, leprosy, metabolic neuropathies, inflammation of the nerve, loss of axon tissue, and demyelination.
More specifically, the high pressures of oxygen delivery result in necrotizing bronchiolitis and alveolar septal injury, further compromising oxygenation of blood.
