Typically, the cancer cell/endothelial cell interactions imply first a selectin-mediated initial attachment and rolling of the circulating cancer cells on the endothelium.
A significant amount of research in this area has been spent exploring methods of nanoparticle-mediated delivery of antineoplastic drugs to tumors in the central nervous system.
Effectively, social content is diffused, and by happenstance authentic experience is displaced by degrees of mediated separation before a subject acquires knowledge of a social phenomenon.