Many of these Costa Rican communities are beginning to the effects of globalization as many plantations are buying up land and invading indigenous areas.
Infections such as omphalitis, pneumonia, gingivitis, and peritonitis are common and often life-threatening due to the infant's inability to properly destroy the invading pathogens.
When invading grey matter structures such as cortex, the neoplastic oligodendrocytes tend to cluster around neurons exhibiting a phenomenon referred to as perineuronal satellitosis.