These are people with immature or weakened immune systems (infants, the elderly, people undergoing cancer therapy, and individuals with acquired immunodeficiency syndrome).
Unlike immunodeficiency caused by malnutrition, life-stage and natural stress need a more comprehensive strategy and can not be addressed simply by correcting nutritional problems.
Factors associated with an increased infection include diabetes mellitus, obesity, malnutrition, smoking, previous infection, rheumatoid arthritis, and immunodeficiency.