Hemorrhagic smallpox also produces a dusky erythema, petechiae, and hemorrhages in the spleen, kidney, serosa, muscle, and, rarely, the epicardium, liver, testes, ovaries and bladder.
In most regions, house rabbits do not require vaccination; however, vaccines are prophylactic against myxomatosis and rabbit hemorrhagic disease where these vaccines are legally permitted.
In the 20th century, rabbit diseases such as myxomatosis and hemorrhagic disease resulted in a dramatic decline of its main prey; outbreaks have been reported into the 2010s.
If bleeding occurs in this process, the resulting effect is a hemorrhagic stroke in the form of subarachnoid hemorrhage, intracerebral hemorrhage or both.