The relation to rheumatic fever was strengthened by many studies that showed that women with normal pregnancies before rheumatic fever developed chorea in subsequent pregnancies.
Se specialized in the study of lung and cardiovascular diseases, and he made contributions involving research of chorea and its association with rheumatic disorders.
Children with chorea appear fidgety and will often try to disguise the random movements by voluntarily turning the involuntary, abnormal movement into a seemingly more normal, purposeful motion.
