It is therefore important that users check the breakthrough permeation times for gloves, and pay scrupulous attention to avoiding contamination when degloving.
It has been demonstrated in various studies, that thiomers exhibit mucoadhesive, permeation enhancing, controlled release as well as enzyme and efflux pump inhibitory properties.
The paracellular pathway allows the permeation of hydrophilic molecules that are not able to permeate through the lipid membrane for the transcellular pathway of absorption.