If the lesion is found on further imaging to be suspicious, it should be surgically excised (via thoracotomy or video-assisted thoracic surgery) to confirm the diagnosis by microscopical examination.
Based on experiments with antitubulin drugs and immunocytochemical analyses at the optical and electron microscopical level the possibility that these tubules consist of tubulin (i.e. eukaryotic protein) has been considered.
This involved the microscopical examination of blood and tissues in which he was one of the first to employ the newly discovered process of photomicrography.
