Between 1990 and 1995, the group attempted several apparently unsuccessful violent attacks using the methods of biological warfare, using botulin toxin and anthrax spores.
Due to its secretive and defense-related nature, it is widely assumed that the institute develops vaccines and antidotes for chemical and biological warfare.
The treaty, essentially, is a gentlemen's agreement amongst members backed by the long-prevailing thought that biological warfare should not be used in battle.