Aberrant DNA methylation patterns have been associated with a large number of human malignancies and found in two distinct forms: hypermethylation and hypomethylation compared to normal tissue.
Aberrant epigenetic mechanisms occur both in chromatin packaging and in localized gene promoter changes that influence transcription of key genes in the cancer process.
Aberrant rains, changed wind patterns, storms, and changes in the marine ecological balance could affect the very survival of the fishing communities, it says.
Aberrant DNA methylation patterns hypermethylation and hypomethylation compared to normal tissue have been associated with a large number of human malignancies.