The typical initial symptoms of a child with hyperammonemia are non-specific: failure to feed, loss of thermoregulation with a low core temperature, and somnolence.
Possible side effects include abdominal pain, allergy, diarrhea, headache, hepatic dysfunction/hepatitis, nausea or vomiting, exacerbation of porphyries, pruritis, rash, somnolence, vertigo, or dizziness.
During childbirth, administration of methoxyflurane produces significantly better analgesia, less psychomotor agitation, and only slightly more somnolence than trichloroethylene.